Primary peritonitis usually occurs in patients with comorbidities previously diagnosed with Birthday Card ascites.However, a primary peritoneal infection in previously healthy patients may also ensue.There has been an increase in reported cases of primary peritonitis due to Streptococcus pyogenes affecting mostly women.It usually presents as a seve
Identification of cortical interneuron cell markers in mouse embryos based on machine learning analysis of single-cell transcriptomics
Mammalian cortical interneurons (CINs) could be classified into more than two dozen cell types that possess diverse electrophysiological and molecular characteristics, and participate in various essential biological processes in the human neural system.However, the mechanism to generate diversity in CINs remains controversial.This study aims to pre
Differences in the curing of [PSI+] prion by various methods of Hsp104 inactivation.
[PSI(+)] yeast, containing the misfolded amyloid conformation of Sup35 prion, is cured by inactivation of Hsp104.There has been controversy as to whether inactivation of Hsp104 by guanidine treatment or by overexpression of the dominant negative Hsp104 mutant, Hsp104-2KT, cures [PSI(+)] by the same mechanism- inhibition of the severing of the prion
Collective instance-level gene normalization on the IGN corpus.
A high proportion of life science researches are gene-oriented, in which scientists aim to investigate the roles that genes play in biological processes, and their involvement in biological mechanisms.As a result, gene names and their related information turn out to be one of the main objects of interest in biomedical literatures.While the capabili
Investigating the evolution of major Northern Hemisphere ice sheets during the last glacial-interglacial cycle
A 2.5-dimensional climate model of intermediate complexity, CLIMBER-2, fully coupled with the GREMLINS Merch 3-D thermo-mechanical ice sheet model is used to simulate the evolution of major Northern Hemisphere ice sheets during the last glacial-interglacial cycle and to investigate the ice sheets responses to both insolation and atmospheric CO<s